sulfur mustard

Study on the effects of sulfur mustard intoxication on lymphocytes in rats

硫芥对大鼠淋巴细胞毒性作用的研究

Sulfur mustard ( SM ) is a blistering chemical warfare agent and has strong antipersonnel effect.

芥子气 属糜烂性毒剂,具有强大的杀伤效应,目前仍是外军主要装备的化学毒剂之一.

Conclusion Lymphocyte could be arrested at G1/ S cycle stage and the growth of cell cycle could be suppressed by sulfur mustard. The mechanism might be carried out through sulfur mustard-induced apoptosis in lymphocyte.

结论硫芥可抑制体外培养的淋巴细胞由G1期进入S期，抑制体外培养的淋巴细胞增殖，通过诱导淋巴细胞凋亡实现作用机制。

Objective To investigate the changes of caspase 3 activity and the interventional effect of tetrapeptide AC DEVD CHO on sulfur mustard induced apoptosis of lymphocyte.

目的探讨caspase3活性在硫芥诱导淋巴细胞凋亡中的变化和其四肽抑制剂Ac DEVD CHO对细胞凋亡的干预作用。

It was reported that about 80 % of the chemical casualties in WW I was sulfur mustard.

据估计一战中芥子气的伤亡率约占化学损伤伤亡率的80%,因此被称为“毒剂之王”.

Objective: To observe the mode of cell death induced by sulfur mustard in the intestinal epithelioid cell line 6 ( IEC 6) in rats.

目的：观察硫芥对大鼠小肠上皮细胞（IEC-6）生长的影响及其引起的细胞死亡方式。

It was reported that about 80% of the chemical casualties in WW I was caused by sulfur mustard.

据估计一战中芥子气的伤亡率约占化学损伤伤亡率的80%，因此被称为毒剂之王。

A mouse ear model of sulfur mustard-induced cutaneous injury

芥子气致小鼠耳廓皮肤损伤模型的建立

Conclusion Sulfur mustard intoxication induces early and long lasting decreases in serum IL2 and IL6 levels and lymphocyte DNA fragmentation in dog peripheral blood.

结论硫芥中毒导致发生早且持续时间较长的犬外周血IL2、IL6含量下降和淋巴细胞DNA损伤。